Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 28, 2026The American Journal of Cardiology

Urgent TEER successfully reduces severe MR as a bail-out after failed surgery in one patient.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Surgical failure and high perioperative risk may limit reintervention options for degenerative mitral regurgitation, particularly in elderly patients with comorbidities, where transcatheter edge-to-edge mitral valve repair may represent a viable bail-out strategy.

Does urgent transcatheter edge-to-edge mitral valve repair (M-TEER) improve severe degenerative mitral regurgitation in a hemodynamically unstable patient after failed surgical repair?

Population

A 79-year-old man with recurrent severe DMR and cardiogenic shock after failed NeoChord surgical repair

Comparison

Urgent M-TEER under VA-ECMO support

Design

Case report

Key result

Urgent transcatheter edge-to-edge mitral valve repair using 2 MitraClip devices successfully reduced severe mitral regurgitation as a bail-out strategy in a 79-year-old man after failed surgery.

Authors

MPMarco PuttiGMGiulia MasieroCFChiara Fraccaro

Discussion

Loading...

Member takes

Overview

May support M-TEER as rescue after failed mitral repair; hypothesis-generating and requires prospective confirmation.

Key Points

  • To evaluate transcatheter edge-to-edge mitral valve repair (M-TEER) as a rescue intervention following surgical repair failure in acute degenerative mitral regurgitation (DMR).
  • Presented case of a 79-year-old man with severe DMR post NeoChord implantation.
  • Performed urgent M-TEER using two MitraClip devices during VA-ECMO support.
  • Utilized advanced echocardiographic assessment and imaging guidance throughout the procedure.
  • Achieved significant reduction of mitral regurgitation without a notable increase in mitral gradient.
  • Patient remained stable after M-TEER, with improved hemodynamic status.
  • Demonstrated feasibility and effectiveness of M-TEER in high-risk surgical candidates.

Study Design

Type

Case Report (n=1)

Structured PICO

Does urgent transcatheter edge-to-edge mitral valve repair (M-TEER) improve severe degenerative mitral regurgitation in a hemodynamically unstable patient after failed surgical repair?

P
Population
79-year-old man with severe degenerative mitral regurgitation (DMR) due to P2 flail, complicated by acute hemodynamic and respiratory deterioration requiring VA-ECMO and CRRT after failed NeoChord surgical repair (n=1)
I
Intervention
Urgent transcatheter edge-to-edge mitral valve repair (M-TEER) with two MitraClip XTW G4 devices under VA-ECMO support
O
Outcome
Reduction of mitral regurgitation without significant increase in mitral gradientsurrogate

Transcatheter edge-to-edge mitral valve repair can serve as a safe and effective bail-out strategy for hemodynamically unstable patients with severe degenerative mitral regurgitation following failed surgical repair.

Cite This Study

Putti et al. (2026) conducted a case report in Acute Degenerative Mitral Regurgitation (n=1). Transcatheter edge-to-edge mitral valve repair (M-TEER) was evaluated on Reduction of mitral regurgitation. Urgent transcatheter edge-to-edge mitral valve repair using 2 MitraClip devices successfully reduced severe mitral regurgitation as a bail-out strategy in a 79-year-old man after failed surgery.

synapsesocial.com/papers/6a025a5c9cddff7633412b9ahttps://doi.org/10.1016/j.amjcard.2026.02.004
View Full Paper
Ask AI
Bookmark
Share