The meta-analytic evaluation of cangrelor in critically ill patients undergoing PCI appropriately utilized crude event data due to the lack of consistent adjusted effect estimates across the limited available studies.
Does intravenous cangrelor improve outcomes compared to oral P2Y12 inhibitors or control in critically ill patients with cardiogenic shock or cardiac arrest undergoing PCI?
This response defends the methodological choices of a meta-analysis on cangrelor in critically ill PCI patients, highlighting the necessity of using crude event data and broad inclusion criteria due to limited available evidence.
Hendrianus et al. (Mon,) conducted a letter in Cardiogenic shock or cardiac arrest undergoing percutaneous coronary intervention. Cangrelor vs. Oral P2Y12 inhibitors or control was evaluated. The meta-analytic evaluation of cangrelor in critically ill patients undergoing PCI appropriately utilized crude event data due to the lack of consistent adjusted effect estimates across the limited available studies.