Concurrent TTS-like angiographic pattern in SCAD patients was associated with a greater risk of in-hospital events including new arrhythmias or heart failure (P=0.010).
Cohort
Does a concurrent Takotsubo-like angiographic pattern increase the risk of in-hospital events in patients with spontaneous coronary artery dissection?
In patients with spontaneous coronary artery dissection, the presence of a concurrent Takotsubo-like angiographic pattern is associated with a higher risk of in-hospital heart failure and new arrhythmias.
valor p: p== 0.010
Background and objectives: Takotsubo syndrome (TTS) and spontaneous coronary artery dissection (SCAD) are both more common in middle-aged women and often share similar triggers, such as emotional or physical stress. This study aimed to examine the characteristics and in-hospital prognosis of patients with SCAD and possible concomitant TTS. Methods: Patients from the iSCAD Registry with completed questionnaires, case report forms, and available coronary angiography and ventriculography adjudicated by a core lab were included. In the absence of follow-up imaging confirming resolution of the wall motion abnormalities a definitive diagnosis of TTS cannot be established, therefore this pattern will be referred to throughout the manuscript as TTS-like angiographic pattern (TVP). Coexistent TVP was defined by classic apical ballooning or wall motion abnormalities discordant with the dissected coronary territory. In-hospital events included recurrent myocardial infarction (MI), cerebrovascular accident, heart failure (HF) requiring diuretics, and new arrhythmias. Patient characteristics and in-hospital events were compared between TVP and non-TVP groups. Results: = 0.010). After multivariable adjustment, coexistent TVP remained associated with in-hospital events. Conclusions: In this SCAD cohort, patients with concurrent TVP had a greater risk of new arrhythmias or HF during hospitalization. Study registration: URL: http://www.clinicaltrials.gov. Identifier: NCT04496687.
Chi et al. (Fri,) conducted a cohort in Spontaneous coronary artery dissection (SCAD) and suspected concurrent Takotsubo syndrome. TTS-like angiographic pattern (TVP) vs. Non-TVP was evaluated on In-hospital events including recurrent myocardial infarction, cerebrovascular accident, heart failure requiring diuretics, and new arrhythmias (p== 0.010). Concurrent TTS-like angiographic pattern in SCAD patients was associated with a greater risk of in-hospital events including new arrhythmias or heart failure (P=0.010).