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May 13, 2026

Anatomical and Functional Outcomes After Pars Plana Vitrectomy for Giant Retinal Tear-Related Detachment: The Manchester GRT Study.

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Authors

PKPeter KiralyTITsveta IvanovaECEvita Evangelia Christou

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Overview

Retrospective cohort study evaluates anatomical and visual outcomes of vitrectomy in retinal detachment cases, suggesting potential implications for treatment choices.

Key Points

  • This study aims to evaluate the anatomical and functional outcomes following primary pars plana vitrectomy for giant retinal tear-related retinal detachment, comparing the effectiveness of gas versus silicone oil tamponade.
  • Retrospective analysis of 110 eyes undergoing primary PPV for GRT-RRD between 2012 and 2024.
  • Comparison of outcomes between silicone oil and gas groups using univariable and propensity score matching analyses.
  • Single surgery anatomical success and best-corrected visual acuity were assessed using logistic and linear regression methods.
  • Single surgery anatomical success (SSAS) was achieved in 88.2% of eyes, and final anatomic success (FAS) in 96.3%.
  • After matching, male sex correlated with higher odds of SSAS (OR 4.54, 95% CI 1.75-11.75; p=0.002), while PVR grade C correlated with lower odds (OR 0.10, 95% CI 0.02-0.45; p=0.003).
  • In macula-on matched eyes, silicone oil was associated with worse final visual acuity (MD +0.179 logMAR, 95% CI 0.018 to 0.341; p=0.030).

Cite This Study

Kiraly et al. (2026) studied this question.

synapsesocial.com/papers/6a04153d79e20c90b444502dhttps://doi.org/10.1016/j.oret.2026.04.028
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