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May 13, 2026AnimalsOpen Access

An Assessment of Anti-Ganglioside Antibodies for the Diagnosis of Avian Ganglioneuritis and Potential Correlation with Gross Lesions, Microscopic Findings and Serologic Titers in Cockatiels Challenged with Parrot Bornavirus

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Authors

BBBianca BückingAGAnna Maria GartnerSHS. Herzog

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Overview

Randomized trial assesses anti-ganglioside antibodies' role in avian ganglioneuritis diagnosis, indicating no significant association.

Key Points

  • To evaluate anti-ganglioside antibodies as diagnostic markers for avian ganglioneuritis in cockatiels.
  • 257 plasma samples from cockatiels experimentally infected with parrot bornavirus were tested for anti-ganglioside antibodies.
  • Results were compared with clinical signs, gross pathological findings, and histopathological results.
  • Blinded testing was performed by a commercial laboratory.
  • 9 out of 25 birds with dilated proventriculi tested positive for anti-ganglioside antibodies (36%).
  • 26 out of 56 birds with histopathological avian ganglioneuritis tested positive (46.43%).
  • No significant association between anti-ganglioside antibody detection and avian ganglioneuritis was found.

Cite This Study

Bücking et al. (2026) studied this question.

synapsesocial.com/papers/6a04153d79e20c90b4445115https://doi.org/10.3390/ani16101466
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