PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
May 14, 2026Artificial Cells Nanomedicine and Biotechnology0 citationsOpen Access

The phytochemical analysis of Carissa macrocarpa , cytotoxic potential of fractions, and the molecular modulation on p53 expression in HT-29 and LS174T cell lines

View Full Paper
SASalma S. AlamriMAMohammad Y. AlfaifiASAli A. Shati

Key Points

  • The research aims to evaluate the cytotoxic effects of phytochemicals from Carissa macrocarpa on colorectal cancer cells through p53 modulation.
  • Conducted phytochemical analysis of Carissa macrocarpa.
  • Assessed cytotoxic potential of fractions in HT-29 and LS174T cell lines.
  • Analyzed modulation of p53 expression due to treatment.
  • Demonstrated significant cytotoxic effects on colorectal cancer cells.
  • p53 expression was effectively modulated, supporting its role in anticancer activity.

Abstract

exerts anticancer effects in colorectal cancer cells by modulating p53 and provides a mechanistic rationale for its therapeutic potential.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Alamri et al. (2026) studied this question.

synapsesocial.com/papers/6a05659da550a87e60a1df6fhttps://doi.org/10.1080/21691401.2026.2668262
Ask AI
Helpful
Bookmark
Share
View Full Paper