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May 14, 2026npj Microgravity0 citationsOpen Access

Telemetric lumbar cerebrospinal fluid pressure monitoring for spaceflight: a novel approach to spaceflight-associated neuro-ocular syndrome research

AEAnders EklundTBTomas BäcklundMWMichael A. Williams

Key Points

  • The aim is to assess a telemetric lumbar ICP monitoring system for studying intracranial pressure changes in microgravity and its implications for SANS.
  • Evaluated a telemetric lumbar ICP monitoring system in a simulated space environment.
  • Analyzed the system's performance, focusing on pulse amplitude and pressure accuracy.
  • Considered long-term stability and overall effectiveness for research purposes.
  • The telemetric system demonstrated promising long-term stability and performance.
  • There were limitations noted in pulse amplitude analysis and pressure underestimation.
  • Despite these issues, the system is recommended for use in SANS research in space.

Abstract

Abstract Spaceflight-associated neuro-ocular syndrome (SANS) poses a significant risk for astronauts, being linked to intracranial pressure (ICP) changes in microgravity. Investigating ICP in space has been challenging. We evaluated a telemetric lumbar ICP monitoring system that shows promise for investigating microgravity-induced intracranial pressure changes in astronauts. Despite limitations in pulse amplitude analysis and pressure underestimation, the system’s long-term stability and overall performance support its recommendation for SANS research in space.

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Cite This Study

Eklund et al. (2026) studied this question.

synapsesocial.com/papers/6a0566bda550a87e60a1ea1fhttps://doi.org/10.1038/s41526-026-00586-0
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