Synthesis and antimitotic activity of 2-phenyl-6-pyridinyl-2 H -pyrazolo4,3- c pyridines

Key Points

• The aim is to evaluate the synthesis and antimitotic effects of new 2-phenyl-6-pyridinyl-2H-pyrazolo[4,3-c]pyridines.
• Synthesis of a series of new compounds based on the described chemical structure.
• Assessment of antimitotic activity through the study of cell morphology and mitotic effects.
• Compound 7f disrupts the microtubule cytoskeleton, leading to altered cell morphology.
• It causes mitotic defects and results in cell death.