Cross-sectional analysis reveals that dietary quality may influence muscular dystrophies via biological aging.
Key Points
This research aims to explore the relationship between the planetary health diet index (PHDI) and muscular dystrophies (MDs), focusing on the mediating role of phenotypic age.
Cross-sectional analysis of 2951 participants from the National Health and Nutrition Examination Survey (2011-2018)
Utilized multivariable logistic regression and mediation analysis
Investigated associations using restricted cubic splines.
Each 10-point increase in PHDI was associated with a 15% reduction in MDs prevalence (OR = 0.85, 95% CI: 0.73-0.99)
Each one-unit increase in phenotypic age was linked to a 7% increase in MDs prevalence (OR = 1.07, 95% CI: 1.01-1.14)
Mediation analysis indicated that phenotypic age accounted for part of the association between PHDI and MDs.