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May 14, 2026Asia-Pacific Journal of Chemical Engineering1 citationsOpen Access

PEG Alternatives in Liposomal Nanocarriers for Sustainable Drug Delivery

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

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CHChandra Has

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Overview

Review assesses novel hydrophilic polymers for liposomal nanocarriers, highlighting sustainable synthesis methods and their implications.

Key Points

  • The review aims to evaluate new hydrophilic polymers as substitutes for PEG in liposomal nanocarriers, focusing on sustainable strategies.
  • Critical assessment of emerging zwitterionic polymers as alternatives to PEG.
  • Highlighting scalable synthesis and lipid conjugation techniques aligned with green chemistry principles.
  • Discussion of theoretical models addressing polymer-lipid interactions and protein corona suppression.
  • Identified zwitterionic polymers offer potential advantages over traditional PEG for long-term in vivo circulation.
  • Explored various intensified processes like microfluidics and supercritical fluids for efficient synthesis.
  • Theoretical insights provided on molecular interactions that can enhance liposomal performance.

Cite This Study

Chandra Has (2026) studied this question.

synapsesocial.com/papers/6a05685ca550a87e60a20e5ehttps://doi.org/10.1002/apj.70257
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