Long-Term Effects of Catheter Ablation vs Medical Therapy in Patients with Atrial Fibrillation and Heart Failure: A Reconstructed Individual Patient Data Meta-Analysis
This research aims to evaluate the long-term effects of catheter ablation versus medical therapy in patients with atrial fibrillation and heart failure.
Reconstructed individual patient data meta-analysis
Included trials comparing catheter ablation and medical therapy
Focus on long-term outcomes and overall mortality
Catheter ablation significantly reduces the risk of hospitalization compared to medical therapy (HR 0.65, 95% CI 0.50-0.85, P=0.002).
Patients undergoing catheter ablation experience a lower incidence of major adverse cardiovascular events (RR 0.70, 95% CI 0.60-0.80, P<0.001).
No significant differences in overall mortality were observed between treatment groups.