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May 15, 2026JAMA0 citations

Antibiotics for Uncomplicated Acute Appendicitis

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DMDimitrios MorisTPTheodore N. Pappas

Key Points

  • This analysis aims to clarify the long-term effectiveness of antibiotics in treating uncomplicated acute appendicitis.
  • 10-year follow-up of the APPAC trial
  • Analysis of treatment outcomes related to antibiotics for appendicitis
  • Antibiotics are a feasible treatment option for uncomplicated acute appendicitis.
  • Long-term data support the efficacy and safety of antibiotics in this context.

Abstract

To the Editor The 10-year follow-up of the APPAC trial provides valuable long-term data supporting antibiotics as a feasible treatment option for uncomplicated acute appendicitis.1 However, several aspects of the analysis and its interpretation warrant clarification.

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Cite This Study

Moris et al. (2026) studied this question.

synapsesocial.com/papers/6a06b81ce7dec685947aa98ahttps://doi.org/10.1001/jama.2026.3808
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