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May 15, 2026Dentistry Journal0 citationsOpen Access

Risk of Edentulism Among Older Adults with Multimorbidity

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RMRolla MiraWSWael Sabbah

Key Result

Each additional chronic condition in older adults was associated with 1.30 times higher odds of developing complete tooth loss over a 6-year period (OR 1.30; 95% CI 1.12-1.52).

Key Points

  • This study examines the relationship between multimorbidity and the risk of becoming edentate among older American adults.
  • Analyzed data from three waves of the Health and Retirement Study, covering participants aged 50 and over.
  • Assessed multimorbidity using data from 2012 and complete tooth loss in 2018.
  • Employed Structural Equation Modelling to evaluate associations.
  • Each additional chronic condition in 2012 was associated with 1.30 times higher odds of edentulism in 2018 (95% CI: 1.12, 1.52).
  • In the SEM, multimorbidity in 2012 was positively associated with edentulism in 2018 (estimate: 0.01, 95% CI 0.01, 0.02).
  • Both smoking and wealth were significantly associated with edentulism and multimorbidity.

Study Design

Type

Cohort (n=6,286)

Structured PICO

Does multimorbidity increase the risk of complete tooth loss in older American adults?

P
Population
6,286 older American adults aged 50 years and over from the Health and Retirement Study (HRS), excluding those with complete tooth loss in 2012.
I
Intervention
Multimorbidity (presence of diabetes, heart conditions, lung diseases, cancer, and stroke)
C
Comparator
Fewer or no chronic conditions
O
Outcome
Complete tooth loss (edentulism) in 2018

Older adults with multimorbidity have a significantly higher probability of becoming edentate over a 6-year period.

Main Result

Effect estimate: OR 1.30 (95% CI 1.12-1.52)

Abstract

Objective: This study aimed to assess whether older American adults with multimorbidity are at higher risk of becoming edentate over time. Methods: We used data from three waves of the Health and Retirement Study (HRS), a longitudinal survey of older American adults aged 50 years and over. Data on multimorbidity was from 2012, while data on complete tooth loss was from 2018. Multimorbidity included five common and serious conditions, namely diabetes, heart conditions, lung diseases, cancer, and stroke. Socioeconomic factor was indicated by total wealth in 2006; behaviour was indicated by smoking in 2012. We used Structural Equation Modelling (SEM) to assess the relationship between multimorbidity in 2012 and complete tooth loss in 2018. Participants with complete tooth loss in 2012 were excluded from the analysis. Results: Among 6286 participants with complete data across all three waves, each additional chronic condition in 2012 was associated with 1.30 times higher odds of edentulism in 2018 (95% CI: 1.12, 1.52). In the SEM, multimorbidity in 2012 was positively associated with being edentate in 2018 (estimate: 0.01, 95% CI 0.01, 0.02); smoking and wealth were also significantly associated with edentulism. Wealth and smoking were also associated with multimorbidity. Conclusions: Older adults with multimorbidity appear to have a higher probability for becoming edentate. The findings highlight the need for oral health promotion activities for those with multimorbidity.

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Cite This Study

Mira et al. (2026) conducted a cohort in Multimorbidity (n=6,286). Multimorbidity vs. Fewer chronic conditions was evaluated on Complete tooth loss (edentulism) (OR 1.30, 95% CI 1.12-1.52). Each additional chronic condition in older adults was associated with 1.30 times higher odds of developing complete tooth loss over a 6-year period (OR 1.30; 95% CI 1.12-1.52).

synapsesocial.com/papers/6a06b81ce7dec685947aaab0https://doi.org/10.3390/dj14050295
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