Preoperative diastolic dysfunction did not predict new-onset postoperative atrial fibrillation (P=0.72), whereas in-stent restenosis ≥70% (OR 6.34; 95% CI 1.68-23.92) was an independent predictor.
Cohort (n=191)
Does preoperative diastolic dysfunction predict new-onset postoperative atrial fibrillation in patients undergoing CABG?
Preoperative diastolic dysfunction is not a predictor of new-onset postoperative atrial fibrillation in patients undergoing CABG, whereas left main disease, severe in-stent restenosis, reduced ejection fraction, and electrolyte imbalance are independent predictors.
valor p: p=0.72
INTRODUCTION: Despite advancements in technique and the increasing number of coronary artery bypass grafting (CABG) procedures, new-onset postoperative atrial fibrillation (POAF) is one of the most common complications following CABG and remains a major concern. The exact mechanism is unclear, but impaired diastolic function may predispose patients to POAF. Thus, this study aims to evaluate preoperative diastolic dysfunction (DD) and associated factors as predictors of new-onset POAF. METHODS: This retrospective cohort study involved patients undergoing CABG surgery who met the inclusion criteria between January 2018 to August 2022. DD was measured through preoperative transthoracic echocardiogram, while new-onset POAF was assessed through continuous electrocardiogram. RESULTS: A total of 191 patients who met the inclusion criteria were enrolled in this study. Data-analysis revealed no significant difference in DD between patients with and without POAF (P = 0.72). Multivariate analysis demonstrated left main coronary artery disease (LMCAD) (odds ratio OR = 2.51; 95% confidence interval CI 1.12 - 5.59; P = 0.02), in-stent restenosis (ISR) ≥ 70% (OR = 6.34; 95% CI 1.68 - 23.92; P < 0.01), reduced ejection fraction ≤ 50% (OR = 2.18; 95% CI 0.94 - 5.06; P = 0.07), and electrolyte imbalance (OR = 2.14; 95% CI 2.91 - 24.75; P < 0.01) as the independent predictors of new-onset POAF. CONCLUSION: DD was not identified as a predictor of new-onset POAF in patients undergoing CABG. The independent predictors identified in this study included male sex, comorbid LMCAD and ISR ≥ 70%, reduced left ventricular ejection fraction ≤ 50%, and postoperative electrolyte imbalance.
Sembiring et al. (Wed,) conducted a cohort in Coronary artery bypass graft surgery (n=191). Preoperative diastolic dysfunction vs. Normal diastolic function was evaluated on New-onset postoperative atrial fibrillation (POAF) (p=0.72). Preoperative diastolic dysfunction did not predict new-onset postoperative atrial fibrillation (P=0.72), whereas in-stent restenosis ≥70% (OR 6.34; 95% CI 1.68-23.92) was an independent predictor.