What question did this study set out to answer?

This study aims to evaluate the association between long-term exposure to wildfire smoke PM2.5 and the risk of heart failure in older adults in the contiguous United States.

May 15, 2026Journal of the American College of CardiologyOpen Access

Long-Term Wildfire Smoke Exposure and Increased Risk of Heart Failure in Older Adults

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Authors

HHHua Hao KXKe Xu DZDanlu Zhang

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Overview

Retrospective cohort study investigates wildfire smoke PM2.5 and heart failure risk in older adults, suggesting health impacts.

Key Points

This study aims to evaluate the association between long-term exposure to wildfire smoke PM2.5 and the risk of heart failure in older adults in the contiguous United States.
Retrospective cohort study of Medicare beneficiaries from 2007 to 2018.
Linked a national cohort to high-resolution PM2.5 exposure estimates for wildfire and nonfire smoke.
Analyzed data using Cox proportional hazard models adjusting for demographic and socioeconomic factors.
HR per 1-μg/m3 increase in smoke PM2.5 is 1.014 (95% CI: 1.007-1.020), higher than nonsmoke PM2.5's HR of 1.005 (95% CI: 1.003-1.006).
Estimated 20,238 additional heart failure cases annually among U.S. older adults due to smoke PM2.5 exposure.
Association stronger in women, Medicaid-eligible individuals, and those in lower income areas.

Cite This Study

Hao et al. (2025) studied this question.

synapsesocial.com/papers/6a073964e08de44c8b637f74 https://doi.org/10.1016/j.jacc.2025.04.058

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May 15, 2026Journal of the American College of CardiologyOpen Access

Long-Term Wildfire Smoke Exposure and Increased Risk of Heart Failure in Older Adults

View Full Paper

Ask AI

Bookmark

Authors

HHHua Hao KXKe Xu DZDanlu Zhang

Discussion

Member takes

Overview

Retrospective cohort study investigates wildfire smoke PM2.5 and heart failure risk in older adults, suggesting health impacts.

Key Points

This study aims to evaluate the association between long-term exposure to wildfire smoke PM2.5 and the risk of heart failure in older adults in the contiguous United States.
Retrospective cohort study of Medicare beneficiaries from 2007 to 2018.
Linked a national cohort to high-resolution PM2.5 exposure estimates for wildfire and nonfire smoke.
Analyzed data using Cox proportional hazard models adjusting for demographic and socioeconomic factors.
HR per 1-μg/m3 increase in smoke PM2.5 is 1.014 (95% CI: 1.007-1.020), higher than nonsmoke PM2.5's HR of 1.005 (95% CI: 1.003-1.006).
Estimated 20,238 additional heart failure cases annually among U.S. older adults due to smoke PM2.5 exposure.
Association stronger in women, Medicaid-eligible individuals, and those in lower income areas.

Cite This Study

Hao et al. (2025) studied this question.

synapsesocial.com/papers/6a073964e08de44c8b637f74 https://doi.org/10.1016/j.jacc.2025.04.058

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