pK's of Nucleic Acid Components as a Function of Temperature

Key Points

• This research aims to study the pK values of deoxynucleic acid components under varying temperatures.
• Examined pK's of -N1H- groups for several deoxynucleic acid components at different temperatures.
• Analyzed thymidine, thymidylic acid, deoxyguanosine, and deoxyguanylic acid (5') in the investigation.
• Calculated △Ĥ's for the ionizations from the obtained pK values.
• Identified temperature-dependent changes in the pK values for the studied components.
• Determined ionization enthalpies (△Ĥ's) related to temperature variations.

Abstract