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May 16, 2026Organic Chemistry Frontiers0 citations

A Generalized Electrochemical Dehydrogenation Approach en route to α-Phosphorylated Amines

NSNayan SahaSCShana ChandranBKBurkhard König

Key Points

  • This research aims to develop a generalized electrochemical approach for forming α-phosphorylated amines from C(sp³)–P bonds.
  • Utilized a novel electrochemical dehydrogenation technique
  • Conducted syntheses involving organophosphorus scaffolds
  • Analyzed bond formation efficiencies and product yields.
  • Successfully formed α-phosphorylated amines under mild conditions
  • Achieved notable improvement in reaction yield compared to traditional methods
  • Demonstrated the versatility of the approach across various substrates.

Abstract

Given the widespread use of organophosphorus scaffolds in several disciplines, the formation of C(sp³)–P bonds is of fundamental importance. Direct access to α-phosphorylated amines still remains challenging, though, because conventional...

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Cite This Study

Saha et al. (2026) studied this question.

synapsesocial.com/papers/6a080a9fa487c87a6a40c897https://doi.org/10.1039/d6qo00588h
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