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January 19, 2026Frontiers in Oncology5 citationsOpen Access

Advances in chimeric antigen receptor-natural killer cell therapy: from mechanisms and preclinical studies to clinical application

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TRTianyuan RenFWFengjiang WangXLXuan Liu

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Abstract

persistence, and the immunosuppressive effects of the tumor microenvironments (TME), as well as their corresponding potential technical solutions, are critically analyzed. By integrating the latest translational insights, this review aims to provide a forward-looking perspective on CAR-NK as a next-generation immunotherapeutic modality.

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Cite This Study

Ren et al. (2026) studied this question.

synapsesocial.com/papers/6a08718cdf3db873981094f1https://doi.org/10.3389/fonc.2025.1759796
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