Poria cocos and Poria cocos polysaccharide chewable tablets: formulation development, quality evaluation and in vivo effects on hyperuricemic nephropathy
Formulation development and evaluation reveal beneficial in vivo effects on hyperuricemic nephropathy, indicating gut microbiota regulation can protect renal health.
Key Points
This research aims to develop and evaluate chewable tablets of Poria cocos polysaccharides for their effects on hyperuricemic nephropathy.
Formulation development of chewable tablets using Poria cocos polysaccharides.
Quality evaluation through in vitro analysis and adjustments in formulation techniques.
In vivo testing of the tablets on hyperuricemic nephropathy with a focus on gut microbiota changes.
Demonstrated renal protective effects in hyperuricemic nephropathy models.
Positive modulation of gut microbiota associated with the treatment.
Report of reliable quality confirming efficacy in supporting renal function.