Background: Artificial intelligence (AI) is transitioning from experimental pilots to core public health functions such as disease surveillance, resource planning, and analysis of social and structural determinants of health. Yet, health data collection and stewardship remain fragmented across the globe; some jurisdictions still rely on paper-based systems, while others operate noninteroperable digital systems that can exacerbate inequities. Treating health data as a global good therefore requires governance that enables innovation while protecting rights, safety, and trust. This study aims to develop a conceptual meso-level capability framework that translates responsible AI principles into organizational practices for public health agencies. Methods: We developed the framework using a targeted narrative synthesis of contemporary governance guidance and documented early implementation experiences, purposively selected to represent major strands of current practice and debate. A structured expert panel consultation (n = 9) was subsequently conducted to assess the face validity and content validity of the proposed framework domains. Results: We propose the Public Health Responsible AI Capability (PH-RAIC) framework, which adapts principles of transparency, accountability, fairness, ethics, and safety to institutional realities faced by public health agencies. PH-RAIC identifies four interdependent capability domains: (1) strategic governance and alignment; (2) data and infrastructure stewardship; (3) participatory design, equity, and public engagement; and (4) lifecycle oversight, learning, and decommissioning. All four domains achieved Content Validity Index (CVI) values ≥ 0.85 in the expert panel consultation. The framework is presented as a conceptual, meso-level model that has undergone preliminary expert validation but requires further empirical testing in real-world agency settings. Conclusions: PH-RAIC links these domains to example practices, diagnostic questions, and illustrative measurement indicators to help agencies navigate efficiency–equity trade-offs and strengthen legitimacy and accountability in AI-enabled public health systems. It offers a validated conceptual basis for future empirical testing and operational readiness tools.
Zahid et al. (Fri,) studied this question.