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May 17, 2026Journal of Proteome Research0 citations

S100 Calcium-Binding Protein P Predicts Early Recurrence and Poor Survival in Distal Cholangiocarcinoma: A Proteomics Study

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HKHyemin KimSHSunghyun HuhIHIn Woong Han

Key Points

  • The study aims to determine the role of S100P as a prognostic biomarker in distal cholangiocarcinoma (dCCA).
  • Conducted a proteomics study to analyze S100P levels in dCCA samples.
  • Evaluated the relationship between S100P levels and early recurrence/survival outcomes.
  • Statistical analysis utilized to establish significance and predictive capacity.
  • S100P levels significantly associated with early recurrence (p=0.002).
  • Higher S100P correlated with poorer overall survival outcomes.
  • Identified as a potential biomarker for postoperative risk stratification.

Abstract

= 0.002). These findings identify S100P as a prognostic biomarker for dCCA, suggesting its clinical utility for postoperative risk stratification and patient management.

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Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/6a095b1b7880e6d24efe0d80https://doi.org/10.1021/acs.jproteome.6c00013
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Integrated Bioinformatics and Experimental Analyses Reveal <scp>S100A12</scp> as a Biomarker and Therapeutic Target in Cholangiocarcinoma2026
  2. 2S100 Calcium-Binding Protein P and Cathepsin E as Key Mediators in Pancreatic Cancer Tumorigenesis2025
  3. 3Prognostic Value of S100 Family mRNA Expression in Hepatocellular Carcinoma2024
  4. 4Overexpression of S100 Calcium-Binding Protein A2 is Associated With Poor Prognosis in Hepatocellular Carcinoma2026
  5. 5Unveiling novel serum biomarkers in intrahepatic cholangiocarcinoma: a pilot proteomic exploration2024 · 2 citations