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May 17, 20260 citations

Effects of Different Vascular Lesions on the Clinical,Pathological, and Prognostic Features of Lupus Nephritis.

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WQWake Ma-Heshati QiaoWYWEN-LING YEWYWei Ye

Key Points

  • This research aims to evaluate how different types of vascular lesions influence the clinical and prognostic features of lupus nephritis.
  • Analyzed intrarenal vascular lesions in lupus nephritis cases
  • Correlated lesions with clinical severity and treatment outcomes
  • Utilized statistical analysis to assess the relationship between lesions and kidney injury
  • Vascular lesions correlate strongly with clinical severity and prognosis in lupus nephritis (p=0.023)
  • Thrombotic microangiopathy (TMA) shows high pathological activity and poor treatment response
  • Atherosclerotic lesions (AS) predict unfavorable long-term renal survival but do not affect immediate treatment response

Abstract

=0.023) respectively. Conclusions Intrarenal vascular lesions are strongly associated with clinical severity and prognosis in LN.LV correlates with acute kidney injury and severe active renal injury,while TMA is the most severe subtype and characterized by high pathological activity,chronicity,poor treatment response,and adverse outcomes.AS,the most common type,does not affect treatment response but predicts unfavorable long-term renal survival.

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Cite This Study

Qiao et al. (2026) studied this question.

synapsesocial.com/papers/6a095b1b7880e6d24efe0e1fhttps://doi.org/10.3881/j.issn.1000-503x.16694
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