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May 17, 2026Pediatric Blood & Cancer

Timeliness and Adherence to Opioid Administration Guidelines for Acute Sickle Cell Pain in Pediatric Patients: A Comparison of Pediatric and Adult Emergency Departments

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Authors

IGIbrahim GwarzoHDHervé DegaDBDavid C. Brousseau

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Overview

Comparison demonstrates higher adherence to opioid guidelines for managing pain in children versus adults, indicating disparities.

Key Points

  • This research investigates the differences in opioid administration timeliness and adherence to national guidelines for pediatric patients with sickle cell disease in emergency departments.
  • Analyzed data from the Epic Cosmos database involving 44,415 emergency department visits between 2019 and 2025.
  • Compared median times for first and second opioid doses in pediatric and adult emergency departments.
  • Calculated adherence rates to national pain treatment guidelines.
  • Median time to first opioid dose was 44 minutes in pediatric EDs vs. 76 minutes in adult EDs.
  • Median time to second opioid dose was 38 minutes in pediatric EDs vs. 78 minutes in adult EDs.
  • Adherence to pain treatment within one hour was 64.9% in pediatric EDs compared to 37.3% in adult EDs.

Cite This Study

Gwarzo et al. (2026) studied this question.

synapsesocial.com/papers/6a095b5d7880e6d24efe1200https://doi.org/10.1002/1545-5017.70410
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