ABSTRACT Background The recent global outbreaks of Mpox, an emerging zoonotic viral disease, highlight sustained transmission in Africa and spread across Europe, challenging public health preparedness among frontline healthcare workers (HCWs). This study aimed to assess the knowledge, attitudes, and practices (KAP) regarding Mpox among hospital nurses and HCWs in Bangladesh and to identify sociodemographic factors influencing KAP outcomes. Methodology A cross‐sectional survey was conducted from October 1, 2024 to November 15, 2024 in eight hospitals in Dhaka district. Hospitals were selected via convenience sampling based on referral status and patient load, and participants were randomly chosen from active healthcare staff across categories. Data were collected using a pretested questionnaire, following a pilot study among 30 nurses and HCWs. Responses were recorded through KoboToolbox, and statistical analyses were performed using univariate and multivariate logistic regression. Results Out of the 200 HCWs approached, 110 provided complete and valid responses and were included in the final analysis. Among those who had heard (60.9%) about Mpox, 47.3% demonstrated good knowledge, 86.4% showed positive attitudes, and 82.7% reported correct preventive practices. Only 60.9% of participants reported having heard about Mpox. Among these, Facebook (29.9%) was the most commonly reported source of Mpox‐related information. Knowledge gaps were evident regarding zoonotic transmission, preventive guidelines, and the protective role of smallpox vaccination. Education level was significantly associated with knowledge (adjusted odds ratio AOR = 4.45; 95% confidence interval CI: 1.83–11.7; p = 0.002). Settlement type was significantly associated with practices, with urban HCWs more likely to report correct preventive measures (AOR = 4.13; 95% CI: 1.10–19.0; p = 0.047). Correlation analysis revealed significant positive associations among KAP ( p < 0.001). Conclusion Targeted training and awareness programs are vital to improve preparedness and infection control among hospital nurses, strengthening the national response to Mpox outbreaks in Bangladesh.
Hossain et al. (2026) studied this question.