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May 17, 2026Journal of Arthroscopy and Joint Surgery0 citations

Risk of Early Complications in Patients Undergoing Bilateral Simultaneous Total Knee Arthroplasty: A Prospective Study

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RPRupesh PrasadCSChetan SoodPGParikshat Gopal

Key Result

Bilateral simultaneous total knee arthroplasty was associated with a 24.1% incidence of early complications at 90 days, with increasing age showing a slight correlation (P=0.047).

Key Points

  • The study aims to evaluate early complications after bilateral simultaneous total knee arthroplasty and their correlation with demographic factors.
  • Evaluated patients undergoing bilateral simultaneous total knee arthroplasty over 5 years; sample size of 1121.
  • 90-day follow-up to assess complications categorized as cardiorespiratory, functional, wound-related, and miscellaneous.
  • Data analysis utilized Python software, with Pearson correlation and gradient boosting for precision, sensitivity, and F1 score.
  • 271 (24.1%) patients developed complications within 90 days post-surgery.
  • 34 (12.5%) cardiorespiratory, 140 (51.6%) functional, 49 (18.1%) wound-related, and 48 (17.8%) miscellaneous complications were recorded.
  • Weak correlations found between early complications and increasing age (P=0.047), BMI, and ASA grade; no cause-effect relationship established.

Study Design

Type

Cohort (n=1,121)

Multicenter

No

Structured PICO

What is the incidence of early complications at 90 days following bilateral simultaneous total knee arthroplasty?

P
Population
1121 patients undergoing bilateral simultaneous total knee arthroplasty over a period of 5 years at a tertiary care hospital
I
Intervention
Bilateral simultaneous total knee arthroplasty
O
Outcome
Early complications at 90 days following surgerysafety

The incidence of early complications within 90 days after bilateral simultaneous total knee arthroplasty is 24.1%, with weak correlations to age, BMI, FCI, and ASA score.

Abstract

Abstract Objectives: The objective of this study was to determine early complications at 90 days following bilateral simultaneous total knee arthroplasty and to find out the correlation between various demographic parameters (age, sex, body mass index BMI, and preoperative hemoglobin), Functional Comorbidity Index (FCI), and American Society of Anesthesiologists (ASA) scores with these complications. Materials and Methods: All the patients undergoing bilateral simultaneous total knee arthroplasty over a period of 5 years at a tertiary care hospital were evaluated in the present prospective interventional study. Patients were followed up 90 days postsurgery and assessed for complications, if any. All complications were divided into four broad categories – cardiorespiratory, functional, wound-related, and miscellaneous (delirium, seizures, pyrexia, gastrointestinal, dyselectrolytemia, etc.). They were also classified into major and minor complications. Data analysis was done using Python software. Pearson correlation was calculated. A t -test was run. Gradient boosting rather than logistic regression was used to calculate precision, sensitivity, and F1 score, as the data were of an unbalanced nature. Results: Out of 1121 patients, 271 (24.1%) developed complications at 90 days follow-up, out of which 34 (12.5%) were cardiorespiratory, 140 (51.6%) were functional, 49 (18.1%) were wound-related, and 48 (17.8%) were miscellaneous. There was a slight increased incidence of developing early complications with increasing age ( P = 0.047), BMI, and ASA grade. FCI showed a negative correlation (−0.0339) with early complications at 90 days. Conclusions: Incidence of developing complications within 90 days after bilateral simultaneous total knee arthroplasty is 24.1%. Age, BMI, FCI, and ASA score show weak correlation in the occurrence of complications post total knee arthroplasty; however, these parameters do not show a cause–effect relationship.

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Cite This Study

Prasad et al. (2026) conducted a cohort in Bilateral simultaneous total knee arthroplasty (n=1,121). Bilateral simultaneous total knee arthroplasty was evaluated on Early complications at 90 days. Bilateral simultaneous total knee arthroplasty was associated with a 24.1% incidence of early complications at 90 days, with increasing age showing a slight correlation (P=0.047).

synapsesocial.com/papers/6a095bdd7880e6d24efe1a88https://doi.org/10.4103/jajs.jajs_45_25
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