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May 17, 2026Anatomy & Cell BiologyOpen Access

Anticancer activity of Hebesu extracts in cancer cell lines

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Authors

EKEun-Jung KimSKSohyun KimNBNayeon Bak

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Overview

Randomized trial explores anticancer effects of Hebesu extract in cancer cell lines, indicating its potential as a natural cancer agent.

Key Points

  • This research aims to evaluate the anticancer activity of Hebesu extract in various human cancer cell lines.
  • Experimental study on MDA-MB-231, HepG2, and A549 cancer cell lines using Hebesu extract (HBS).
  • Assessment of cell viability, apoptosis markers, and oncogenic gene expression post-treatment with HBS.
  • Utilization of TdTomato fluorescence imaging to evaluate cytotoxic effects based on concentration and exposure time.
  • HBS treatment led to a significant dose-dependent reduction in cell viability across all tested cancer cell lines.
  • Increased expression of apoptosis-related markers and reduced Ki-67 expression were observed post-HBS treatment.
  • Caspase-3 levels were elevated, while oncogenic genes (SMO, KRAS, BRAF) were downregulated.

Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/6a095c6d7880e6d24efe28d6https://doi.org/10.5115/acb.26.031
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