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May 17, 2026Turkiye Klinikleri Journal of Dental Sciences0 citationsOpen Access

Genetic Polymorphisms and Their Impact on Dental Caries Susceptibility: Bibliometric Analysis of Clinical Implications for Oral Health

SASemih Ercan AkgünÖHÖmer HATİPOĞLU

Key Points

  • The analysis aims to explore the research landscape of genetic polymorphisms related to dental caries.
  • Conducted a bibliometric analysis using the Web of Science Core Collection.
  • Included 173 studies focusing on human polymorphisms and dental caries.
  • Utilized VOSviewer for co-authorship, keyword co-occurrence, and source co-citation mapping.
  • Publication output increased sharply post-2010, peaking between 2015 and 2018.
  • Usa and Brazil emerged as primary contributors with significant outputs from China and Türkiye.
  • Identified key thematic areas include enamel formation genes, taste-related genes, and SNP-based susceptibility.

Abstract

Objective: This bibliometric analysis aims to map the scientific landscape of human polymorphisms in dental caries by identifying key trends, prolific contributors, and research collaborations. Material and Methods: On July 23, 2024, the Web of Science Core Collection was searched using the topic query topic search (TS)=(polymorphism) AND TS=(dental caries), without year or language restrictions. The search retrieved 312 records after document-type filtering and title/abstract screening, 173 studies focusing on human polymorphisms and dental caries were included. Bibliometric analyses were performed in VOSviewer using co-authorship, keyword co-occurrence, and source co-citation mapping. Results: Publication output increased markedly after 2010 and peaked between 2015 and 2018. The United States and Brazil were the leading contributors, while China and Türkiye also showed substantial research output. Vieira was the most productive author and occupied a central position in co-authorship networks. Keyword and co-citation analyses identified enamel formation genes, tasterelated genes, early childhood caries, and single nucleotide polymorphism (SNP)-based susceptibility research as the dominant thematic areas. Conclusion: This study shows that research on human polymorphisms and dental caries has expanded substantially since 2010 and is primarily centered on enamel formation genes, taste-related genes, early childhood caries, and SNP-based susceptibility. While the United States leads the field, growing contributions from Brazil, China, and Türkiye reflect the increasing internationalization of this research area.

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Cite This Study

Akgün et al. (2026) studied this question.

synapsesocial.com/papers/6a095c6d7880e6d24efe28e9https://doi.org/10.5336/dentalsci.2025-112701
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