Key points are not available for this paper at this time.
-CaMKII signaling functioned as parallel pro-differentiation modules, with reduced sustained β-catenin signaling associated with neuronal lineage commitment. These cellular and molecular changes were accompanied by improved motor/sensory recovery and electrophysiological conduction. Collectively, this engineered exosome-loaded hydrogel provides a combinatorial biomaterial platform that reshapes the inhibitory SCI niche and harnesses endogenous neural stem cell-based repair.
Li et al. (Fri,) studied this question.