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May 20, 2026Clinical Nuclear Medicine0 citations

Mild 18F-PSMA-1007 Uptake in a Giant Bone Island

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ZXZhengguang XiaoTCTing ChenADAisheng Dong

Key Points

  • To explore the characteristics of a giant bone island using 18F-PSMA-1007 PET/CT imaging.
  • Case report of one patient with a giant bone island in the left femoral head
  • 18F-PSMA-1007 PET/CT imaging utilized to assess PSMA uptake
  • Measurement of the lesion's diameter and characteristics on CT
  • The giant bone island measured 2.2 cm in maximum diameter on CT
  • Mild uptake of 18F-PSMA-1007 was observed in the sclerotic lesion
  • Potential correlation between PSMA expression and osteoblastic activity was suggested

Abstract

A giant bone island, defined as having a diameter >2.0 cm, is rare. We describe 18 F-PSMA-1007 PET/CT findings in a patient with a giant bone island in the left femoral head. The giant bone island appeared as a well-defined sclerotic lesion measuring 2.2 cm in maximum diameter on CT and showed mild 18 F-PSMA-1007 uptake on PET. The increased PSMA uptake may suggest a possible PSMA expression related to osteoblastic activity.

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Cite This Study

Xiao et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5064f03e14405aa9c2b9https://doi.org/10.1097/rlu.0000000000006428
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