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May 20, 2026American Journal of Respiratory and Critical Care Medicine

C42-46 The Bleeding Never Ends: A Superwarfarin Story

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Authors

ETE ThomasANA Nawab

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Overview

Case Presentation reveals severe bleeding complications in a 65-year-old male exposed to superwarfarin, indicating urgent intervention needs.

Key Points

  • This case highlights the complications and challenges associated with superwarfarin toxicity.
  • Case presentation of a 65-year-old male with a history of lung disease and methamphetamine use.
  • Laboratory evaluations included INR, PT, PTT, and imaging studies to diagnose pulmonary complications.
  • Treatment involved high-dose IV Vitamin K and supportive care with blood products.
  • Patient exhibited severe respiratory distress and copious hemoptysis with an INR of 7.01 and acute anemia (hemoglobin 9 g/dL).
  • Treatments had limited effectiveness; patient showed no improvement in coagulation profile despite aggressive management.
  • Isolated factor X deficiency was found, complicating the diagnosis and treatment approach.

Cite This Study

Thomas et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5089f03e14405aa9c54fhttps://doi.org/10.1093/ajrccm/aamag162.3018
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