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May 20, 2026American Journal of Respiratory and Critical Care Medicine

C48-15 Successful Management of Transfusion-related Acute Lung Injury (TRALI) With Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Support in a Post-surgical Patient

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Authors

FRF RavatHSH SekharamahantiHPH Patel

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Overview

Case report demonstrates improved oxygenation in severe TRALI using VV-ECMO, suggesting it can be lifesaving.

Key Points

  • This case highlights the successful management of severe TRALI using VV-ECMO support in a post-surgical patient.
  • A 65-year-old male post-surgery presented with severe TRALI symptoms after multiple blood transfusions.
  • VV-ECMO was initiated after clinical evaluation indicated worsening hypoxemia and respiratory failure.
  • Supportive care was provided, including optimizing ventilator settings and monitoring blood gases.
  • Post-initiation of VV-ECMO, the patient's oxygenation improved significantly over 48 hours.
  • The patient was decannulated and extubated shortly after stabilization of oxygen levels.
  • Timely recognition and use of VV-ECMO were crucial for recovery from TRALI.

Cite This Study

Ravat et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5089f03e14405aa9c55bhttps://doi.org/10.1093/ajrccm/aamag162.159
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