Randomized trial examines omega-3 fatty acids' effects on lung injury markers in mid-adulthood, suggesting protective benefits.
Key Points
The research aims to explore the associations between omega-3 fatty acids and early molecular and structural markers indicative of chronic lung disease.
Secondary analyses from the CARDIA Lung Study with 2,697 participants
Examined plasma omega-3 fatty acid levels at Year 20 and lung impairment markers at Year 25
Used multivariable logistic and linear regression models to adjust for various covariates
Each 1-unit log increase in omega-3 fatty acids reduced odds of having the highest CT-defined interstitial abnormalities by 28% (OR = 0.72; 95% CI: 0.53–0.97)
A 1-unit log increase in omega-3 levels correlated with a 0.29 reduction in respiratory susceptibility score (p < 0.001)