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May 20, 2026Scientific ReportsOpen Access

J-shaped relationship between physical activity and frailty risk in adults with sleep disorders: the additional protective role of the weekend warrior pattern

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Authors

YSY SunMYMin YinLZLibin Zhou

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Overview

Randomized trial demonstrates reduced frailty risk in adults with sleep disorders through physical activity, suggesting significant implications for health.

Key Points

  • The research aimed to explore the relationship between physical activity and frailty risk in adults with sleep disorders.
  • Examined data from 2,706 participants with sleep disorders from the National Health and Nutrition Examination Survey (2007–2018).
  • Physical activity was measured using the Global Physical Activity Questionnaire and expressed as metabolic equivalent minutes per week.
  • Utilized multivariable logistic regression and nonlinear modeling for analysis.
  • Identified a J-shaped association between physical activity and frailty, with lower odds of frailty (OR = 0.50, 95% CI: 0.33–0.76) below 1,037 MET-min/week.
  • Participants in the highest physical activity quartile showed lower odds of frailty compared to the lowest quartile (OR = 0.65, 95% CI: 0.46–0.91).
  • The 'weekend warrior' pattern was associated with lower odds of frailty (OR = 0.49, 95% CI: 0.25–0.96).

Cite This Study

Sun et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5114f03e14405aa9d5a2https://doi.org/10.1038/s41598-026-53372-z
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