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May 21, 2026American Society of Clinical Oncology Educational Book

Biomarkers for Diagnosis, Risk Stratification, and Immunotherapy of Pediatric Solid Tumors

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Authors

EKEwa KościelniakKJKatie JanewaySGStephen Gottschalk

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Overview

Review highlights biomarkers for diagnosis, treatment selection, and immunotherapy in pediatric solid tumors, indicating evolving strategies.

Key Points

  • The aim is to review the role of biomarkers in diagnosing, risk stratifying, and developing immunotherapy for pediatric solid tumors.
  • Conducted a comprehensive review of existing literature on biomarkers in pediatric solid tumors
  • Examined the role of liquid biopsies and target selection for therapy
  • Discussed challenges in establishing gold standard methods for biomarkers and immunotherapy
  • Biomarkers enhance diagnostic accuracy and assist in risk stratification for pediatric solid tumors.
  • Liquid biopsies show promise as prognostic biomarkers, though standard methods are not yet defined.
  • Targeted therapy and immunotherapy based on biomarkers are less frequently utilized.

Cite This Study

Kościelniak et al. (2026) studied this question.

synapsesocial.com/papers/6a0ea127be05d6e3efb5f904https://doi.org/10.1200/edbk-26-519040
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Biomarkers of Treatment Response in Paediatric Medulloblastoma2026
  2. 2Immunotherapy for pediatric solid tumors: overcoming biological barriers through rational multimodal combinations2026 · 3 citations
  3. 3Immunotherapeutic advances in pediatric neuroblastoma: Overcoming resistance through biomarker-guided combinations2026 · 5 citations
  4. 4Abstract IA010: Opportunities and challenges for liquid biopsies in pediatric oncology2024
  5. 5Liquid Biopsy Biomarkers for Predicting and Monitoring Immunotherapy Response in Lung Cancer2026 · 1 citations