Chronic HBV infection was associated with a shift towards vagotonia, while MASLD showed a tendency to sympathicotonia compared to normotonia in healthy controls.
Cross-Sectional (n=85)
How does the balance of the sympathetic and parasympathetic nervous system differ among patients with chronic HBV infection, MASLD, and healthy controls?
The Kerdo Vegetative Index reveals distinct autonomic nervous system imbalances in different chronic hepatopathies, suggesting its potential as a non-invasive diagnostic adjunct.
Chronic hepatopathies present one of the important medical issues in Moldova, occupying a leading place in terms of incidence and severity. The aim was to study the balance of the sympathetic and parasympathetic nervous system in patients with chronic hepatopathies of various etiologies. A total of 59 patients were examined: I-st group: 34 patients with chronic HBV infection, II-nd group: 25 with Metabolic Dysfunction-Associated Steatosic Liver Disease (MASLD), 26 practically healthy individuals formed the control group (CG). All participants were assessed for diastolic blood pressure (DBP), pulse rate (PR) and Kerdo Vegetative Index (KVI). The highest average DBP values were observed in Group I, the lowest - in CG. The highest average PR values were determined in Group II, in Group I and CG were significantly lower. Average KVI values revealed the prevalence of vagotonia in individuals with chronic HBV infection, normotonia with a tendency to sympathicotonia in patients with MASLD and normotonia in CG. In patients with chronic HBV viral infection, the vagosympathetic balance was shifted towards vagotonia, and in patients with MASLD, a tendency to sympathicotonia was noted. The KVI indicator can be used as an additional non-invasive method for diagnosing chronic hepatopathies.
Berezovscaia et al. (Wed,) conducted a cross-sectional in Chronic hepatopathies (n=85). Chronic HBV infection and MASLD vs. Healthy controls was evaluated on Balance of the sympathetic and parasympathetic nervous system (assessed by DBP, PR, and Kerdo Vegetative Index). Chronic HBV infection was associated with a shift towards vagotonia, while MASLD showed a tendency to sympathicotonia compared to normotonia in healthy controls.