BACKGROUND: Overlapping signal intensities in conventional MRI limit parotid tumor characterization, necessitating advanced techniques like arterial spin labeling (ASL) to assess physiological parameters such as vascularity. OBJECTIVES: To evaluate the diagnostic performance of ASL in differentiating parotid gland tumors by quantifying tumor blood flow ASLm (mean) and ASLmax (maximum) and determining optimal cutoff values correlated with histopathological findings. METHODS: Forty-seven patients (20 pleomorphic adenomas PA, 20 Warthin tumors WT, 7 malignant) underwent standardized 1.5 T MRI protocols and ASL prior to parotidectomy. Quantitative ASL values were obtained from lesions and contralateral tissue. Statistical comparisons and ROC analyses were performed to identify diagnostic cutoff values. RESULTS: = 0.002). CONLUSIONS: While ASL perfusion MRI effectively differentiates common benign parotid tumors, its limitations in malignancy evaluation necessitate its integration into a multiparametric MRI protocol for a more reliable preoperative diagnosis.
Alkan et al. (Tue,) studied this question.