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May 25, 2026Food Science & Nutrition0 citationsOpen Access

Research Progress of Puerarin and Its Benefits in Nonalcoholic Fatty Liver Disease: A Bibliometric Analysis

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WWWei WangXLXin Liu

Key Points

  • This research aims to evaluate the progress of puerarin in addressing nonalcoholic fatty liver disease (NAFLD).
  • Conducted bibliometric analysis using VOSviewer and CiteSpace software to analyze research trends.
  • Explored puerarin’s toxicity, pharmacokinetics, and pharmacological activity in NAFLD treatment.
  • Provided references for future research directions based on current findings.
  • Identified a growing focus on puerarin in natural products for treating NAFLD.
  • Documented puerarin's pharmacological benefits and mechanisms in mitigating NAFLD effects.
  • Highlighted the necessity for safe and effective treatment options for NAFLD.

Abstract

ABSTRACT With the development of society and the economy, nonalcoholic fatty liver disease (NAFLD) has become a major chronic disease in contemporary society. Finding a safe, effective, and economical method is essential for the treatment of NAFLD. Puerarin is a unique component of pueraria. In recent years, puerarin has gradually become the focus of research in the natural products field. This article analyzes the research trend of puerarin through VOSviewer software and CiteSpace software. This will be conducive to deepening the understanding of puerarin. Meanwhile, this article also explores the toxicity, pharmacokinetics, and pharmacological activity of puerarin, as well as the mechanism and progress of puerarin in the treatment of NAFLD, which also provides valuable references for future research in this field.

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6a13e8030e02ee3982d32ac5https://doi.org/10.1002/fsn3.71926
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice2024 · 28 citations
  2. 2Up-regulation of thioredoxin system by puerarin inhibits lipid uptake in macrophages2020 · 32 citations
  3. 3Role of the Inflammasome in Liver Disease2021 · 279 citations
  4. 4The effects of Puerarin on CYP2D6 and CYP1A2 activities In vivo2010 · 31 citations
  5. 5Puerarin prevents LPS-induced acute lung injury via inhibiting inflammatory response2018 · 65 citations