Positive childhood experiences and associations with plasma inflammatory markers in early adulthood

• It is relatively unknown whether positive childhood experiences impact inflammation in early adulthood. • No significant associations between PCE score and age 24 inflammation markers were found. • ‘High frequency contact with family and friends’ was associated with lower CRP levels. • Trauma did not modify the PCE-inflammation relationship. • PCEs and trauma may work via different mechanisms in relation to distal health outcomes.