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May 27, 2026FEBS Letters

Atomic force microscopy‐based nanomechanical signatures as cancer biomarkers in a nutshell

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Authors

ASAndreas Stylianou

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Overview

Review summarizes AFM techniques for cancer diagnosis and extends applications for liquid biopsy, suggesting innovative advances.

Key Points

  • Review the use of atomic force microscopy (AFM) to understand cancer mechanics and identify potential biomarkers.
  • Discusses principles of atomic force microscopy and its application to tumor biopsy analysis.
  • Highlights emerging techniques for mechanophenotyping in liquid biopsy.
  • Explores broader applicability, including potential use in pulmonary fibrosis.
  • Identifies nanomechanical signatures that differentiate cancer states at single-cell and tissue levels.
  • Presents challenges to clinical translation of AFM techniques for widespread use.

Cite This Study

Andreas Stylianou (2026) studied this question.

synapsesocial.com/papers/6a168b770c924ddd1bd5a3dehttps://doi.org/10.1002/1873-3468.70367
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