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May 28, 2026Neuro-Oncology AdvancesOpen Access

A deep learning algorithm for fully automated volumetric measurement of meningioma burden

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Authors

MCMason C. ClevelandAKAlbert E KimTMThomas N McNeal

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Overview

Randomized trial developed a deep learning model for volumetric assessment of meningioma burden, suggesting improved accuracy and efficiency.

Key Points

  • The aim is to develop a deep learning model for fully automated 3D segmentation and volumetric assessment of meningioma burden.
  • Utilized 450 post-contrast T1-weighted brain MRIs from 104 patients.
  • Trained a U-Net model with a joint Dice-cross entropy loss function.
  • Included diverse meningioma grades and treatment statuses in the dataset.
  • Achieved a median Dice of 0.741 and HD95 of 26 mm on high-grade tumors.
  • Achieved a median Dice of 0.848 and HD95 of 1.41 mm on low-grade tumors.
  • Generalized well to external data with a median Dice of 0.923 and HD95 of 2.24 mm.

Cite This Study

Cleveland et al. (2026) studied this question.

synapsesocial.com/papers/6a17dbbe3fad632b0f9d86f4https://doi.org/10.1093/noajnl/vdag137
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