This research aims to explore how the exercise hormone irisin helps alleviate symptoms of rheumatoid arthritis by targeting dysfunctional mitochondria.
Examined the role of irisin in reducing arthritis symptoms in experimental models.
Evaluated mitochondrial function and its relationship to inflammation.
Investigated therapeutic strategies leveraging irisin's effects on mitochondria.
Irisin was associated with a significant reduction in rheumatoid arthritis symptoms.
The treatment led to improved mitochondrial function and decreased inflammation markers.
Findings support the potential of irisin as a therapeutic strategy for arthritis.
Abstract
). Our study elucidated the underlying mechanism through which exercise alleviated experimental arthritis and offered a feasible therapeutic strategy for RA.