Guanidine-Based Azines from N-Heterocyclic Carbene (NHC)-Derived Selenoureas and Diazo Compounds: Synthesis, Structural Diversification, and Biological Evaluation

Key Points

• The aim is to synthesize guanidine-based azines and evaluate their biological properties.
• Synthesis of guanidine-based azines via reactions involving N-heterocyclic carbenes, selenoureas, and diazo compounds.
• Structural diversification techniques were applied to explore variations in molecular configurations.
• Biological evaluation to assess the medicinal potential of synthesized compounds.
• Successfully synthesized a variety of guanidine-based azines.
• Demonstrated promising biological activity, indicating potential therapeutic applications.
• Structural diversity was achieved through multiple synthetic routes, enhancing compound library.