Why the study?
Evidence on hypertension risk factors in South Africa is scattered across study designs, limiting clinical decision support.
What are the strongest risk factors for hypertension in South Africa?
Comparison
Hypertension risk factors
Design
Systematic review and meta-analysis
Key result
Advanced age (OR 3.67; 95% CI 1.7-7.6) and diabetes (OR 1.85; 95% CI 1.39-2.46) were identified as the strongest risk factors for hypertension in South Africa.
Authors
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Prioritizes older adults and diabetics for hypertension screening in South Africa; extends meta-analytic evidence to guide local prevention.
Meta-Analysis (n=49,058)
Yes
What are the strongest risk factors for hypertension in South Africa?
Effect estimate: OR 3.67 (95% CI 1.7-7.6)
Advanced age and diabetes are the strongest risk factors for hypertension in South Africa, highlighting priority groups for screening and prevention.
Nweke et al. (2026) conducted a meta-analysis in Hypertension (n=49,058). Risk factors (advanced age, diabetes, low education, ethnicity, socioeconomic status) was evaluated on Hypertension risk (OR 3.67, 95% CI 1.7-7.6). Advanced age (OR 3.67; 95% CI 1.7-7.6) and diabetes (OR 1.85; 95% CI 1.39-2.46) were identified as the strongest risk factors for hypertension in South Africa.
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