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May 29, 2026Clinical Autonomic Research0 citationsOpen Access

Indications, contraindications, and step-by-step methodology for performing carotid sinus massage in patients presenting with syncope

FLFrederik J. de LangeMBMichele BrignoleDBDavid G. Benditt

Key Points

  • This consensus document aims to improve the use of carotid sinus massage for diagnosing unexplained reflex syncope.
  • Developed by an international panel of experts on syncope.
  • Included practical guidance for performing carotid sinus massage in various clinical settings.
  • Addressed barriers to the effective use of carotid sinus massage in diagnostics.
  • Highlighted the underuse of carotid sinus massage in clinical practice.
  • Showed a need for standardized methodology to enhance diagnostic yield.
  • Emphasized the potential for mechanism-based personalized treatment in syncope patients.

Abstract

Abstract Carotid sinus massage (CSM) is essential in evaluating recurrent unexplained reflex syncope, as it uniquely identifies cardioinhibitory forms that other tests may miss. CSM is largely underused in clinical practice outside dedicated syncope facilities and, when performed, its execution varies, as does the interpretation of results. Underuse affects the diagnostic yield of CSM in the syncope evaluation, thereby denying patients mechanism-based personalized treatment. There are several barriers to the proper use of CSM in the work-up of patients with unexplained syncope. To address these important limitations, an international panel of experts in the field of syncope provide herein a consensus document with the aim of offering practical guidance for the indications, contraindications, and methodology for performing carotid sinus massage in general and dedicated syncope facilities and in the emergency department.

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Cite This Study

Lange et al. (2026) studied this question.

synapsesocial.com/papers/6a192d4afab5b468c44162d5https://doi.org/10.1007/s10286-026-01218-z
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