7091 Background: Performance status assessments may overlook important health vulnerabilities in adults with cancer. While geriatric assessment (GA) systematically evaluates multiple domains including physical function, cognition, psychological health, comorbidity, and nutrition, it has been predominantly studied in older adults. We evaluated the prevalence and patterns of GA-identified deficits among adults of all ages initiating systemic therapy for lymphoma. Methods: Adults with lymphoma enrolled in a prospective registry at an academic cancer center from 2018-2025 completed a modified Cancer and Aging Research Group (CARG) GA at treatment initiation. The assessment included validated measures across eight domains: mobility (Timed Up and Go), falls history, instrumental activities of daily living (IADLs), medication burden, comorbidities, weight loss, cognition (Blessed Orientation-Memory-Concentration test), and psychological health (Mental Health Index-13). Karnofsky Performance Status (KPS) was documented. Prevalence of deficits was compared between adults 14 seconds 5 (2-12) 4 (1-14) 6 (2-19) 1.0 *Reflects missing values (1 each for weight loss, MHI13, daily medications, and comorbid conditions, 10 for BOMC, and 16 for TUG). **P-values from Fisher's exact test.
Jensen et al. (Thu,) studied this question.