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May 29, 2026Open Access

Evaluation of Thyroid Functions in Patients with Chronic Kidney Disease and its Relation to the Disease Severity

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Authors

AAAmal AhmedMEMaha EsmailHEHend El-Shamy

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Overview

Case-control study evaluates thyroid functions in chronic kidney disease, indicating severity correlations.

Key Points

  • The aim is to evaluate thyroid functions in patients with chronic kidney disease and relate these findings to disease severity.
  • Case-control study with 90 Egyptian subjects above 18 years old.
  • Thyroid function tests (FT3, FT4, TSH) were measured and compared among different CKD stages.
  • Correlations with fasting blood sugar, creatinine levels, and estimated GFR were analyzed.
  • FT3 levels significantly decreased in CKD patients (Group I) compared to controls (Group II) (p < 0.01).
  • FT4 levels showed a significant decrease (p < 0.01) and TSH levels significantly increased in CKD patients (p < 0.01).
  • Negative correlation found between FT3 and creatinine; FT4 positively associated with eGFR levels.

Cite This Study

Ahmed et al. (2025) studied this question.

synapsesocial.com/papers/6a192dd1fab5b468c4416bcchttps://doi.org/10.21608/aimj.2025.446430
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