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May 29, 2026Communications Medicine0 citationsOpen Access

Estimating investment costs to improve hypertension care in Lagos, Nigeria

CDCharlotte M. DieterenGGGloria P. Gómez-PérezABAtze Bellaar

Key Result

Providing complete guideline-based hypertension care in Lagos, Nigeria, requires an average annual investment gap of 120 USD per patient and is associated with a 5-6 mmHg reduction in systolic blood pressure.

Key Points

  • This study aims to estimate the investments needed to enhance hypertension care in Lagos, Nigeria.
  • Analyzed medical records from 1249 hypertension patients across 74 public and private facilities.
  • Combined patient-level data with facility-level cost data to calculate required investments for guideline-based care.
  • Used linear random effects regression to evaluate the relationship between care completeness and blood pressure change.
  • Adherence to recommended care resulted in a 5–6 mmHg decrease in systolic blood pressure.
  • Average annual investment needed for complete hypertension care is $300 million, equating to $5000 to $13,000 per saved life year.
  • High medication costs account for about 70% of total care expenses, highlighting significant health access issues.

Study Design

Type

Observational (n=1,249)

Multicenter

Yes

Structured PICO

What is the required investment to deliver guideline-based hypertension care and its impact on blood pressure in patients in Lagos, Nigeria?

P
Population
1249 hypertension patients across 74 public and private facilities in Lagos State, Nigeria
I
Intervention
Guideline-based hypertension care (adherence to consultations and medications)
C
Comparator
Current standard of care (undertreated)
O
Outcome
Investment required to deliver guideline-based care and associated blood pressure changesurrogate

Providing guideline-based hypertension care in Lagos, Nigeria requires an average annual investment of USD 120 per patient, primarily driven by medication costs, necessitating systemic changes like bulk purchasing and expanded insurance.

Limitations

  • Retrospective analysis of real-world data
  • High rate of missing data for key risk factors (BMI available for only 1% of patients, smoking status not recorded, total cholesterol available for only 2.6%)
  • Extrapolation to state level relies on assumptions about patient distribution across facility types

Abstract

Low- and middle-income countries (LMICs) house 66% of all hypertension patients, many of whom are undertreated, leading to severe health risks and higher healthcare costs. This study examined the required investments to improve hypertension control in Lagos, Nigeria, using real-world medical records and cost data. We analyzed routine medical records from 1249 hypertension patients across 74 public and private facilities in Lagos State and combined these with facility-level cost data to estimate the investment required to deliver guideline-based care. Patient-level gaps were extrapolated to the state level using prevalence-based scenarios, and linear random effects regression was used to assess associations between care completeness and blood pressure change. We found that adherence to consultations and medications according to guidelines was significantly associated with a 5–6 mmHg reduction in systolic blood pressure. These reductions correspond to a 6–14% decrease in cardiovascular complication risk and would require an average annual investment of USD 120 per patient. Medications are the main cost driver. Statewide, providing complete care for all hypertension patients would require a yearly investment of 300 million, or 5000 to 13, 000 per saved life year. The identified required investments are currently far outside an acceptable range when compared to the Gross Domestic Product (GDP) of Lagos State, Nigeria. To make chronic care investments feasible, hypertension management must become more efficient, including reducing high medication costs through bulk purchasing, adopting innovative, group-based blended care models, and increasing health insurance coverage. In Nigeria, more than one in three adults has high blood pressure, yet many people are not diagnosed or do not receive adequate treatment. This study estimated how much extra investment is needed to provide recommended care for people with high blood pressure in Lagos State, Nigeria. We used routine medical records from 1249 patients treated in 74 public and private clinics, and we collected real prices for clinic visits, counseling, and medicines. We found that a full year of care based on medical guidelines costs about 148 USD per patient, and medicines make up around 70% of this costs. The gap between current care and recommended care is large with 120 USD, and even larger for uninsured patients with 142 USD. It is concerning that medicines make up such a large share of the total costs, as this limits access for many patients which increases health inequalities. Reducing drug prices through bulk purchasing and expanding health insurance coverage could make life-saving care for high blood pressure more affordable. Dieteren et al. analyze real world medical record and cost data from hypertension patients in Lagos, Nigeria, to estimate the investment required to deliver guideline-based care. They find a large treatment gap, high medication driven costs, and investment needs that exceed commonly used cost effectiveness thresholds.

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Cite This Study

Dieteren et al. (2026) conducted an observational in Hypertension (n=1,249). Guideline-based hypertension care vs. Current incomplete care was evaluated on Average annual investment gap per patient for complete guideline-based hypertension care. Providing complete guideline-based hypertension care in Lagos, Nigeria, requires an average annual investment gap of 120 USD per patient and is associated with a 5-6 mmHg reduction in systolic blood pressure.

synapsesocial.com/papers/6a192e4efab5b468c4417659https://doi.org/10.1038/s43856-026-01660-0
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