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May 29, 2026Chirality

Geometric Stabilization of Biomolecular Chirality in Open Systems

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Authors

VDVicente Domínguez-Arca

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Overview

Randomized trial reveals a geometric mechanism stabilizing biomolecular chirality, suggesting a new understanding of homochirality.

Key Points

  • To investigate a geometric mechanism that stabilizes biomolecular chirality in open systems.
  • Propose a local chirality marker based on a scalar triple product.
  • Analyze how right-handed helices act as orientation-preserving sectors in configuration space.
  • Explore the impact of irreversible evolution on the persistence of chirality.
  • Chirality inversion pathways are dynamically suppressed due to their low dimensionality in the configuration space.
  • Established chirality tends to persist and amplify under nonequilibrium conditions.
  • The proposed framework suggests that homochirality emerges from thermodynamic and geometric interactions rather than primordial asymmetries.

Cite This Study

Vicente Domínguez-Arca (2026) studied this question.

synapsesocial.com/papers/6a192e68fab5b468c441771ehttps://doi.org/10.1002/chir.70107
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