Chronic effects of baroreflex activation therapy: a tale of the unexpected

Key Points

• The aim is to explore the chronic effects of baroreflex activation therapy on physiological responses and sympathetic activity.
• Randomized trial design
• Assessment of physiological responses before and after therapy
• Evaluation of sympathetic activity changes.
• Baroreflex activation therapy led to significant improvements in physiological responses (p<0.05).
• Reduction in sympathetic activity observed over the chronic follow-up period.
• Unexpected outcomes included variances in blood pressure regulation.