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Engagement in physical activity (PA) is a key health-promoting behavior in the prevention and management of chronic kidney disease (CKD). However, evidence regarding the associations between domain-specific PA and CKD remains limited. This study examined the relationships between different PA domains and CKD. Data were obtained from a large population-based survey. PA was self-reported and categorized into transportation-related (TPA), occupational (OPA), and leisure-time PA (LTPA). Multivariable logistic regression, restricted cubic spline models, and subgroup analyses were used to assess associations between PA domains and CKD. Among 24,492 participants, meeting PA guidelines through OPA and LTPA was associated with lower odds of CKD (OPA: OR 0.81, 95% CI 0.72–0.91; LTPA: OR 0.86, 95% CI 0.75–0.98), whereas no significant association was observed for TPA. Non-linear dose–response relationships were identified between CKD risk and OPA, LTPA, and total PA. Subgroup analyses suggested that the protective association of OPA was not consistent across all populations. Higher levels of OPA and LTPA were inversely associated with CKD risk, underscoring the potential relevance of domain-specific PA in relation to kidney health from a public health perspective.
Luo et al. (Tue,) studied this question.